Top Sci-Fi Show on HBO: Mushroom-Centric Series (Not The Last Of Us)

When Adult Swim’s “Common Side Effects” first debuted in 2024, it felt like a silver lining after HBO Max canceled “Scavengers Reign,” another visually stunning show created by Joseph Bennett. While the two shows share some similarities, “Common Side Effects” has carved its own path, making it one of the most captivating animated series in recent years. Interestingly, this show also shares a key theme with HBO’s hit series “The Last of Us” – mushrooms. But don’t worry, there’s no need to pick sides on which show is the best sci-fi story about mushrooms (both are available for streaming on HBO Max along with other binge-worthy miniseries). However, personally, I lean towards “Common Side Effects” over “The Last of Us.”

What makes “Common Side Effects” stand out is that it’s not a dystopian horror tale like “The Last of Us.” Instead, it’s a complex sci-fi conspiracy thriller that delves into the enigmatic Blue Angel fungus, rumored to be a cure for all diseases. The show follows protagonist Marshall Cuso (portrayed by Dave King), a brilliant botanist who stumbles upon this miraculous fungus in the Peruvian Highlands. As Cuso unravels the fungus’s healing powers, he faces fierce opposition from corporate giants like Reutical Pharmaceuticals, determined to suppress his discovery at all costs.

Despite having a smaller fanbase compared to “The Last of Us,” “Common Side Effects” is a gem in its own right. Critics have showered praise on this thought-provoking and witty series since its premiere, boasting a perfect critic score on Rotten Tomatoes. With its unique animation style, intriguing themes, and bold critique of the healthcare industry, “Common Side Effects” has set itself apart from the crowd.

What draws me most to the show is its blend of humor, scientific exploration, and mind-bending visuals. The mysterious “little guys” that appear when characters ingest the mushroom add an extra layer of intrigue and charm to the storyline, making you want to unravel their secrets alongside the main characters. Shows like “Common Side Effects” and “Scavengers Reign” mark an exciting shift in adult animation, pushing the boundaries beyond typical comedy series like “Family Guy” or “Rick and Morty.”

With Season 2 already confirmed, “Common Side Effects” has the opportunity to further explore its universe and solidify its place among the top series in its genre. It’s a captivating ride that promises to take viewers on a psychedelic journey filled with laughter, conspiracy, and endless possibilities.